15/08/2015-present Associate Professor, University of Macau
15/08/2011-15/08/2015 Assistant Professor, University of Macau
01/08/2002-31/08/2005 Associate Professor, Zhejiang University
Education & Training
B. Med, Zhejiang University, 01/09/1989-31/08/1994
M. Phil, The Chinese University of Hong Kong, 01/08/2000-31/07/2002
PhD, University of Hong Kong, Hong Kong, 01/09/2005-31/08/2008
Research Grants
Mechanistic studies on the development of cerebral small vessel diseases and therapeutic potentials of omega-3 polyunsaturated fatty acids in the treatment of cerebral small vessel diseases and vascular cognition impairment (Macao Science and Technology Development Fund; Project Code: FDCT 020/2017/A1; Duration: 2017, 08-2020, 07). PI.
Driving metabolite clearance from the brain to maintain its homeostasis via activating the Glymphatic System (Multi-year research grant from the University of Macau; Project Code: MYRG2016-00184-ICMS-QRCM; Duration: 2017, 01-2019, 12). PI.
Roles and action mechanisms of SENP3 in autism (FDCT-NSFC; Project Code: FDCT 039/2017/AFJ; Duration: 2018, 01-2020, 12). PI.
Study of neprilysin gene therapy targeting the glymphatic pathway for the treatment of Alzheimer’s disease and cerebral amyloid angiopathy. (MYRG; Project code: MYRG2018-00242-ICMS; Duration: 2018, 09-2021, 08). PI.
Selected Publication
Luo C, Ren H, Yao X, Shi Z, Liang F, Kang JX, Wan JB, Pei Z, Su KP, Su H*. Enriched Brain Omega-3 Polyunsaturated Fatty Acids Confer Neuroprotection against Microinfarction. EBioMedicine. 2018 Jun; 32:50-61.
Shi Z, Xie Y, Ren H, He B, Wang M, Wan J, Yuan TF, Yao X, Su H*. Fish oil treatment reduces chronic alcohol exposure induced synaptic changes. Addiction Biology. 2018, doi:10.1111/adb.12623.
Chong CM, Ai N, Ke M, Tan Y, Huang Z, Li Y, Lu JH, Ge W, Su H*. Roles of Nitric Oxide Synthase Isoforms in Neurogenesis. Mol Neurobiol. 2018 Mar;55(3):2645-2652.
Huang X, Chen Y-Y, Shen Y, Cao Y, Li A, Liu Q, Li Z, Zhang L-B, Dai W, Tan T, Arias-Carrion O, Xue Y-X, Su H* and Yuan T-F*. Methamphetamine abuse impairs motor cortical plasticity and function. Molecular Psychiatry 2017 Sep;22(9):1274-1281.
Ren H, Yang Z, Luo C, Zeng H, Li P, Kang JX, Wan JB, He C, Su H*. Enriched Endogenous Omega-3 Fatty Acids in Mice Ameliorate Parenchymal Cell Death After Traumatic Brain Injury. Mol Neurobiol. 2017 Jul;54(5):3317-3326.
Ren H, Luo C, Feng Y, Yao X, Shi Z, Liang F, Kang JX, Wan JB, Pei Z, Su H*. Omega-3 polyunsaturated fatty acids promote amyloid-β clearance from the brain through mediating the function of the glymphatic system. FASEB J, 2017 Jan;31(1):282-293.
Luo C, Liang F, Ren H, Yao X, Liu Q, Li M, Qin D, Yuan TF, Pei Z, Su H*. Collateral blood flow in different cerebrovascular hierarchy provides endogenous protection in cerebral ischemia. Brain Pathology. 2017 Nov;27(6):809-821.
Shi Z, Ren H, Huang Z, Peng Y, He B, Yao X, Yuan T, Su H*. Fish oil prevents Lipopolysaccharide -induced depressive-like behavior by inhibiting neuroinflammation. Mol Neurobiol. 2017 54:7327-7334.
Shi Z, Ren H, Luo C, Yao X, Li P, He C, Kang JX, Wan JB, Yuan TF, Su H*. Enriched Endogenous Omega-3 Polyunsaturated Fatty Acids Protect Cortical Neurons from Experimental Ischemic Injury. Mol Neurobiol. 2016 Nov;53(9):6482-6488.
Luo C, Yao X, Li J, He B, Liu Q, Ren H, Liang F, Li M, Lin H, Peng J, Yuan TF, Pei Z, Su H*. Paravascular pathways contribute to vasculitis and neuroinflammation after subarachnoid hemorrhage independently of glymphatic control. Cell Death Dis. 2016 Mar 31;7:e2160.
Tan Y, Ren H, Shi Z, Yao X, He C, Kang JX, Wan JB, Li P, Yuan TF, Su H*. Endogenous Docosahexaenoic Acid (DHA) prevents Aβ1–42 oligomers induced neuronal injury. Mol Neurobiol. 2016 Jul;53(5):3146-53. doi: 10.1007/s12035-015-9224-0.
