Dr. Steven T. Proulx

Academic Degree(s)

Ph.D.

 

E-mail

steven.proulx@pharma.ethz.ch

 

Current Position

  • Senior Scientist / Group Leader,Institute of Pharmaceutical Sciences, ETH Zürich, Zürich, Switzerland

 

Professional Experience

  • 02/2013- Senior Scientist / Group Leader,Institute of Pharmaceutical Sciences, ETH Zürich, Zürich, Switzerland

 

Education & Training

  • 01/2008-01/2013 Post-Doctoral Fellow, Institute of Pharmaceutical Sciences, ETH Zürich, Zürich, Switzerland, Laboratory of Prof. Michael Detmar, MD
  • 07/2003-12/2007 PhD in Biomedical Engineering, Department of Orthopedics, University of Rochester, Rochester, NY
  • 09/1998-05/1999 MS in Biomechanical Engineering, Stanford University, Palo Alto, CA

 

Awards

  • 2018 GRC in Lymphatics, Best Poster Award
  • 2012 Andrew Moisoff Young Investigator Award
  • 2009-2011 Whitaker Foundation International Scholar

 

Research Grants

  • 2017-2019 Synapsis Foundation and Heidi Seiler-Stiftung

 

Selected Publication

  • Ma Q, B Ineichen, M Detmar, ST Proulx. “Outflow of cerebrospinal fluid is predominantly through lymphatic vessels and is reduced in aged mice.” Nature Communications. 2017; 8:1434 (DOI: 10.1038/s41467-017-01484-6).
  • Proulx ST, Q Ma, D Andina, JC Leroux, M Detmar. “Quantitative measurement of lymphatic function in mice by noninvasive near-infrared imaging of a peripheral vein” JCI Insight 2017; 2 (1): e90861.
  • Chong C, F Scholkmann, S Bachmann, P Luciani, JC Leroux, M Detmar, ST Proulx. “In vivo visualization and quantification of collecting lymphatic vessel contractility using near-infrared imaging” Scientific Reports 2016; 6, Article number: 22930
  • Escobedo N, ST Proulx, S Karaman, M Dillard, N Johnson, M Detmar, G Oliver. “Restoration of lymphatic function rescues obesity in Prox1 haploinsufficient mice” JCI Insight 2016; 1 (2):e85096.
  • Brambilla D, ST Proulx, P Marschalkova, M Detmar, JC Leroux. “Microneedles for the noninvasive structural and functional assessment of dermal lymphatic vessels.” Small 2016; 12 (8):1053-61.
  • Gousopoulos E, ST Proulx, J Scholl, M Uecker, M Detmar. “Prominent lymphatic vessel hyperplasia with progressive dysfunction and distinct immune cell infiltration in lymphedema” American Journal of Pathology 2016; 186 (8), 2193-2203.
  • Karaman S, D Buschle, P Luciani, JC Leroux, M Detmar, ST Proulx. “Decline of lymphatic vessel density and function in murine skin during aging.” Angiogenesis 2015; 18 (4), 489-498.
  • Aspelund A, S Antila, ST Proulx, TV Karlsen, S Karaman, M Detmar, H Wiig, K Alitalo. “A dural lymphatic vascular system that drains brain interstitial fluid and macromolecules.” The Journal of Experimental Medicine 2015; 212 (7), 991-999.
  • Proulx ST, P Luciani, A Christiansen, S Karaman, KS Blum, M Rinderknecht, JC Leroux, M Detmar. “Functional near-infrared imaging reveals rerouting of lymphatic tumor drainage after sentinel lymph node metastasis.” Biomaterials 2013; 34:5128-37.
  • Proulx ST, P Luciani, S Derzsi, M Rinderknecht, V Mumprecht, JC Leroux, M Detmar.  “Quantitative imaging of lymphatic function with liposomal indocyanine green.” Cancer Research 2010; 70: 7053-7062.