Prof. Cai Song




Academic Degree(s)





Current Position

  • Director and professor of Research Institute for Marine Drugs and Nutrition, Guangdong Ocean University, P. R. China. 


Professional Experience

  • Jan. 2011-Sept. 2013 Director and Professor, Chinese Academy Engineer Institute for the Development of Endangered Medicinal Resources in South-West China.
  • July 2005-July, 2010 Canada Research Chair, National Research Institute of Nutrisciences and Health and Department of Biomedical Science, AVC, UPEI, Canada.
  • Sept 2001-Sept. 2004, Assistant Professor, Department of Psychiatry, Univ. of British Columbia, Canada.


Education & Training

  • 1995-1997, Postdoctoral Researcher in the Neuroscience Research Institute, Carleton University and Psychology School, University of Ottawa, Canada.
  • 1994-1995, Postdoctoral Researcher in Department of Psychiatry, McGill University, Canada.
  • 1991-1994, PhD in Psychoneuroimmunology, the National University of Ireland.



  • Aug.2017, National Leading Scientist Certificate, Shenzhen City, China
  • Nov. 2016, Fellow and Life Member of International Stress and Behaviour Society. US.
  • Aug, 2012, “Famous Oversea Professor”, Chinese Ministration of Education (1 million RMB), China.
  • June 2005, Canada Research Chair II in Psychoneuroimmunology awarded by the Prime Minister and the Government of Canada.
  • Feb. 1999, Pfizer 1998 Psychiatry Award, by Pfizer International Pharmaceuticals, London, UK.


Research Grants

  • 2016-2019, Development of omega-3 fatty acids in the treatment of depression and neurodegeneration. Department of Science and Technology, Guangdong Province, China. ¥8,000,000.
  • 2014-2018,The role of microglia-induced inflammation and changed membrane function in chronic stress model of depression. National Natural Science Foundation of China. ¥700,000.
  • 2014-2018, The modulation of neuron-immune network and function in unsaturated fatty acid gene transit and knock out mice. Taiwan National Science Council. TWD 6,200,000.
  • 2014-2018, Canada-China International platform. Department of Education, Guangdong Government, China. ¥360,000.
  • 2011-2016, The mechanism of IL-1-induced neurodegeneration and memory impairment. National Natural Science Grant. ¥590,000.


Committee & Membership

  • World Research Journal of Clinical Nutrition (2013-) Associate Editor
  • Frontiers in Cellular Neuroscience (2015- ), Review Editor
  • Chinese core periodical “Chinese Medicine Process and Health”(2016-), Chief Editor


Selected Publication

  • Song C. Liu BP, Zhang YP, Peng ZL, Wang JJ, Kalueff AV. Modeling consequences of prolonged strong unpredictable stress in zebrafish: complex effects on behavior and physiology. Prog Neuropsycho Biol Psychia 81:384-394,2017.
  • Zhang YP,Jiao GL, Song C, Gu S, Brown RE, Zhang JZ, Zhang PC, Gagnon J, Locke S, Stefanova R, Pelletier C, Zhang Y, Lu HY. An Extract from Shrimp Processing By-Products Protects SH-SY5Y Cells from Neurotoxicity Induced by Aβ25–35. Marine Drugs, 15 (3): 83, 2017.
  • Dong Y, Xu M, Kalueff AV, Song C. Dietary eicosapentaenoic acid normalizes hippocampal omega-3 and 6 polyunsaturated fatty acid profile, attenuates glial activation and regulates BDNF function in a rodent model of neuroinflammation induced by central interleukin-1β administration. Eur J Nutr. 2017 May 18 (in press).
  • Song C, Berridge KC, Kalueff AV. 'Stressing' rodent self-grooming for neuroscience research. Nat Rev Neurosci. 17(9):591, 2016.
  • Song C, Shieh CH, Wu YS, Kalueff A, Gaikwad S, Su KP. The role of omega-3 polyunsaturated fatty acids eicosapentaenoic and docosahexaenoic acids in the treatment of major depression and Alzheimer’s disease: acting separately or synergistically? Prog. Lipid Res.2016, 62:41-54.*
  • Luchtman DW, Meng Q, Wang X, Shao D, Song C. Omega-3 fatty acid eicospaentaenoic acid attenuates MPP+ induced neurodegeneration in fully differentiated human SH-SY5Y and primary mesencephalic cells. J. Neurochem. 124(6):855-68,2013.
  • Song C, Zhang Y, Dong Y. Acute and subacute IL-1beta administrations differentially modulate neuroimmune and neurotrophic systems: possible implications for neuroprotection and neurodegeneration. J. Neuroinflammation 2013, 10:59.
  • Song C, Zhang XY, Manku M. Increased phospholipase A2 activity and inflammatory response but decreased nerve growth factor expression in a depression model olfactory bulbectomized rats: Effects of chronic ethyl-eicosapentaenoate treatment," J Neurosci 29: 14-22, 2009.
  • Song C, Phillips AG, Leonard BE, Horrobin DF. Omega-3 fatty acid and RU 486 reverse IL-1-induced memory impairment in rats: a glucocorticoid involved mechanism. Mol. Psychiatry 9: 630-638, 2004.
  • Song C, et al. Cytokines in detoxified patients with chronic alcoholism without liver disease: increased monocytic cytokine production. Biol. Psychiat. 45: 1212-1216, 1999.